This case study highlights outcomes from a specialized Massive Open Online Course (MOOC) on Caring for Children Moving Alone: Protecting Unaccompanied and Separated Children. The MOOC was developed by an interagency network led by the IFRC and International Social Services (ISS). The free, six-week MOOC aims to increase the knowledge and support improved practice of tens of thousands of local front-line workers who make decisions about the care and best interest of children on the move every day.